The story begins with a substance known in the game as black fog. This fog is known for consuming people, towns, and other signs of civilization or life, nothing ever to escape from within. In Lost Kingdoms, the fog invades the land of Argwyll, home of the main character Katia, who is also the princess of this kingdom. The fog has been terrorizing the land for a long time, and Katia's father - the king - eventually ventured out to help try and deal with the deadly substance. However, since her father hadn't returned in some time, Katia soon leaves to find him.
Generations after the events of Lost Kingdoms, Katia of Argwyll is now remembered as a legendary queen. The heroine of this story is Tara Grimface, a reserved member of a guild of thieves, who is trying to find her way in a dangerous world. While she is an outcast even among her allies, they respect and fear her because she possesses a True Runestone that allows Tara to use powerful magic cards in battle. Tara becomes embroiled in events that will eventually shape the lands around her as she travels with the Band of the Scorpion on a mission to steal the runestones crafted in the caverns of Kendaria. It is here that Tara first happens across the monster responsible for creating these runestones to which she later finds to be the body of the god of harmony. Through the journey Tara undertakes she will eventually find herself on a path to discovering her former self. Although, if she is to uncover the secret of her mysterious origins, she will have to overcome her distrust of others.